Figure 5.
Motility effect sizes for tumor cells in 2D or 3D. (a) Cohen's d (effect size) delineations for small (≥0.2, <0.5), medium (≥0.5, <0.8), and large (≥0.8) effect sizes. (b) Cohen's d calculated for percent migrating cells when stimulated with CXCL12 versus vehicle control of patient‐derived glioma stem cell lines in 2D and 3D. (c) Cohen's d for SkBr3 breast cancer cells when stimulated with epidermal growth factor or treated with inhibitors of integrin‐β 1 or integrin‐α 2 in 2D (for speed of cell migration) or 3D (for invasion into collagen gels)