Table 2.
HRs and 95% CI for dietary LA in quintiles and per 5% energy and incident type 2 diabetes in 3,257 post-MI patients from the Alpha Omega Cohort
| Quintiles of dietary LA | Per 5% energy | P value | ||||||
|---|---|---|---|---|---|---|---|---|
| Q1 (n = 651) | Q2 (n = 652) | Q3 (n = 651) | Q4 (n = 652) | Q5 (n = 651) | P-trend* | |||
| Median dietary LA, % energy | 3.5 | 4.6 | 5.6 | 6.8 | 8.8 | |||
| Cases | 37 | 30 | 34 | 39 | 31 | |||
| Model 1† | 1.00 | 0.79 (0.49, 1.28) | 0.90 (0.56, 1.43) | 1.04 (0.66, 1.64) | 0.81 (0.50, 1.31) | 0.72 | 1.01 (0.70, 1.44) | 0.96 |
| Model 2‡ | 1.00 | 0.80 (0.49, 1.29) | 0.95 (0.59, 1.51) | 1.12 (0.71, 1.76) | 0.88 (0.54, 1.44) | 0.97 | 1.09 (0.76, 1.58) | 0.64 |
| Model 3§ | 1.00 | 0.72 (0.44, 1.19) | 0.86 (0.51, 1.45) | 1.01 (0.56, 1.81) | 0.78 (0.36, 1.72) | 0.84 | 1.18 (0.59, 2.35) | 0.64 |
% energy, percentage of total energy intake, excluding energy from alcohol.
P values for trend were obtained by assigning each patient median dietary LA for the category and this value was modeled as continuous.
Model 1 was adjusted for age (continuous; years), sex (men/women), and Alpha Omega Trial treatment code (four categories).
Model 2: model 1 plus physical activity (three categories), smoking status (three categories), educational level (four categories), BMI (continuous; kg/m2), family history of type 2 diabetes (yes/no), total energy intake (excluding calories from alcohol, continuous; kcal/day), alcohol consumption (four categories), dietary fiber (g/day; continuous), and dietary cholesterol (mg/day; continuous).
Model 3 (substitution of SFA and TFA for LA): model 2 plus dietary protein (% energy; continuous), carbohydrates (% energy; continuous), n-3 PUFAs (% energy; continuous), and cis-MUFAs (% energy; continuous).