Table 3.
HRs and 95% CI for plasma LA in quintiles and per 5% and incident type 2 diabetes in 3,257 post-MI patients from the Alpha Omega Cohort
| Quintiles of plasma LA | Per 5% | P value | ||||||
|---|---|---|---|---|---|---|---|---|
| Q1 (n = 652) | Q2 (n = 650) | Q3 (n = 651) | Q4 (n = 653) | Q5 (n = 651) | P-trend* | |||
| Median plasma LA, % | 43.9 | 47.6 | 50.1 | 52.8 | 56.3 | |||
| Cases | 49 | 38 | 31 | 31 | 22 | |||
| Model 1† | 1.00 | 0.76 (0.50, 1.16) | 0.63 (0.40, 0.98) | 0.61 (0.39, 0.96) | 0.42 (0.26, 0.70) | <0.001 | 0.73 (0.63, 0.85) | <0.001 |
| Model 2‡ | 1.00 | 0.74 (0.48, 1.14) | 0.64 (0.40, 1.00) | 0.60 (0.38, 0.94) | 0.44 (0.26, 0.75) | 0.001 | 0.73 (0.62, 0.86) | <0.001 |
P values for trend were obtained by assigning each patient median plasma LA for the category and this value was modeled as continuous.
Model 1 was adjusted for age (continuous; years), sex (men/women), and Alpha Omega Trial treatment code (four categories).
Model 2: model 1 plus physical activity (three categories), smoking status (three categories), educational level (four categories), BMI (continuous; kg/m2), family history of type 2 diabetes (yes/no), total energy intake (excluding calories from alcohol, continuous; kcal/day), alcohol intake (four categories), dietary fiber (g/day; continuous), and dietary cholesterol (mg/day; continuous).