Table 3. Clinical and laboratory features of children with influenza A (pH1N1’09) virus infection during pandemic and post-pandemic seasons.
| Pandemic season | Post-pandemic season | ||
|---|---|---|---|
| Clinical feature | Median [interquartile range] | Median [interquartile range] | p (Mann-Whitney U) |
| Mean age (yrs) | 4.5 [8] | 3.5 [7] | 0.140 |
| Duration of disease prior to hospitalization (days) | 3.0 [1] | 4.0 [3] | 0.001* |
| Length of hospital stay (days) | 4.0 [3] | 6.0 [3] | 0.013* |
| Mean maximum temperature (ºC) | 39.5 [0.8] | 39[0.8] | 0.276 |
| Erythrocyte sedimentation rate (mm/h) | 15 [14] | 20 [28] | 0.326 |
| Leukocyte count (x109/L) | 8.5 [4.9] | 9.5 [9.3] | 0.480 |
| C-reactive protein (mg/L) | 46.6 [55.7] | 48.7 [61.0] | 0.827 |
| Creatine kinase (U/L) | 91 [75] | 134 [246] | 0.374 |
| Laboratory findings | n (%) | n (%) | p (χ2) |
| Liver damage | 6 (9.4) | 7 (15.9) | 0.486 |
| Abnormal electrocardiography | 18 (28.2) | 14 (31.8) | 0.075 |
| Patients treated with antiviral agents | 43 (67.2) | 36 (81.8) | 0.092 |
| Patients treated with antibiotics | 23 (35.9) | 21 (47.7) | 0.220 |
| Patients treated in Intensive Care Unit | 13 (20.3) | 4 (9.1) | 0.220 |
| Died | 0 | 1 (2.3%) | 0.226 |
| Total | 64 (37.9%) | 44 (26.4%) |
*Statistically significant (p<0.05)