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. 2020 Jan 20;20:17. doi: 10.1186/s12866-020-1706-1

Table 2.

Characteristics* of the patients successfully genotyped (N = 57)

Category Parameters Characteristics Total [N (% or IQR)] #P-Values
Demographics Sex Female 39 (68) 0.042
Male 18 (32)
Age at baseline Median (IQR) years 34 (30–42) 0.921
Marital Status Single 12 (21) 0.663
Married 29 (51)
Divorced/Separated 4 (7)
Widowed 12 (21)
Education None 6 (11) 0.770
Primary 14 (25)
Secondary 18 (32)
Tertiary 19 (33)
Occupation Not Employed 15 (26) 0.338
Employed 42 (74)
Clinical Parameters First-line Backbone NRTI AZT 34 (60) 0.978
TDF 16 (28)
bOthers 7 (12)
First-line Second NRTI 3TC 39 (68) 0.666
FTC 18 (32)
First-line NNRTI NVP 43 (75) 0.071
EFV 14 (25)
Time on First-line ART (Months) ART Initiation to F1 21 (12–36) 0.217
F1 to FC 5 (4–6) 0.086
FC to Viral Re-suppression 5 (3–10) 0.118
Laboratory Parameters Baseline CD4+ cells/μL < 200 38 (67) 0.780
200–350 17 (30)
> 350 2 (4)
Median (IQR) 155 (105–235)
Baseline Viral Load (VL), copies/mL ≤100,000 36 (63) 0.774
> 100,000 18 (32)
Unknown 3 (5)
Median (IQR) 43,587 (13128–176,990)
VL at initial failure (copies/mL) Median (IQR) 9113 (3680–49,670) 0.768
VL at confirmatory failure (copies/mL) Median (IQR) 16,266 (2042–4,002,513) 0.454
HIV-1 Subtype G 25 (44)

0.261

Grouped as G, CRF02_AG and Others

CRF02_AG 23 (40)
A 3 (5)
CRF06_cpx 3 (5)
J 1 (2)
C 1 (2)
Recombinant of A1, G 1 (2)

aDemographic characteristics of those successfully genotyped were not significantly different from those not genotyped; F1 First VL ≥ 1000 cp/mL; FC Second VL ≥ 1000 cp/mL. #P-value is for difference in patient characteristic and drug resistance. IQR Interquartile range. bOthers = Backbone NRTI was switched