Table 3.
Association between childhood BMI with lifetime MDD1 in an Icelandic population (N = 889)
| Lifetime MDD (cases/n) | Model 12 | Model 23 | |||||
|---|---|---|---|---|---|---|---|
| Odds Ratio 95% CI | P-value | Odds Ratio 95% CI | P-value | ||||
| Continuous BMI | |||||||
| BMI age 8 (kg/m2) | 32/664 | 1.15 | (0.88–1.50) | 0.32 | 1.11 | (0.84–1.47) | 0.46 |
| BMI age 13 (kg/m2) | 30/708 | 1.14 | (0.98–1.32) | 0.10 | 1.12 | (0.96–1.32) | 0.14 |
| BMI categories | |||||||
| Normal or underweight age 8 | 24/641 | 1.00 | (reference) | 1.00 | (reference) | ||
| Obese or overweight age 8 | 4/23 | 4.304 | (1.34–13.76) | 0.01 | 4.034 | (1.16–13.96) | 0.03 |
| Normal or underweight age 13 | 27/683 | 1.00 | (reference) | 1.00 | (reference) | ||
| Obese or overweight age 13 | 3/25 | 3.00 | (0.84–10.73) | 0.09 | 2.65 | (0.69–10.26) | 0.16 |
BMI Body mass index, MDD Major Depressive Disorder, GDS Geriatric depression scale, CI Confidence intervals.
1 measured at age ~ 75 y
2 Model 1 = adjusted for sex
3 Model 2 = Model 1 + education, physical activity, smoking status and alcohol use
4 Significant at P-value <0.05