Table 2.
Diagnostic performance of the 2010 and 2017 McDonald criteria for multiple sclerosis.
| TP (n) | FP (n) | FN (n) | TN (n) | Sensitivity | Specificity | Accuracy | |
|---|---|---|---|---|---|---|---|
| DIS | |||||||
| 2010 | 38 | 9 | 33 | 12 | 53.5 (53.3–54.4) | 54.5 (53.4–55.6) | 53.8 (53.4–54.5) |
| 2017 | 61 | 15 | 10 | 6 | 85.9 (85.6–86.6) | 27.3 (26.4–28.6) | 72.0 (71.6–72.7) |
| DIT | |||||||
| 2010 | 12 | 3 | 43 | 18 | 18.8 (18.4–19.7) | 94.1 (93.5–94.7) | 38.5 (38.3–39.7) |
| 2017 | 38 | 8 | 10 | 8 | 79.2 (78.5–79.6) | 47.1 (46.7–49.3) | 70.8 (70.4–71.5) |
| DIS + DIT | |||||||
| 2010 | 9 | 0 | 62 | 21 | 14.6 (13.9–14.9) | 100.0 | 36.9 (35.8–37.1) |
| 2017 | 36 | 8 | 12 | 8 | 75.0 (74.2–75.6) | 47.1 (46.7–49.5) | 67.7 (67.2–68.6) |
Values given within parentheses represent 95% confidential intervals.
DIS, dissemination in space; DIT, dissemination in time; FN, false negative; FP, false positive; TP, true positive; TN, true negative.