Table 2.
Comparison of features between NMOSD-associated SSM lesions and NMOSD-associated LETM lesions.
| SSM lesions (n = 14) | LETM lesions (n = 38) | p value | |
|---|---|---|---|
| Median length, Median (range) | 2 (1–2.5) | 6 (3–13) | <0.001 |
| T1WI hypointensity, no. (%) | 1/14 (7%) | 18/38 (47%) | 0.009 |
| Sagittal imaging | |||
| cervical cord involved only, no. (%) | 6/14 (43%) | 11/38 (29%) | 0.506 |
| thoracic cord involved only, no. (%) | 8/14 (57%) | 16/38 (42%) | 0.366 |
| expanded over cervical and thoracic cord, no. (%) | 0/14 (0%) | 11/38 (29%) | 0.025 |
| Axial imaging* | |||
| Centrally located, no. (%) | 11/14 (79%) | 33/38 (87%) | 0.666 |
| Transversally extensive lesions, no. (%) | 12/14 (86%) | 34/38 (89%) | 0.655 |
| Grey matter involved, no. (%) | 14/14 (100%) | 38/38 (100%) | – |
| Grey matter, lateral columns and dorsal columns involved simultaneously, no. (%) | 12/14 (86%) | 33/38 (87%) | 1.000 |
| Enhancement on T1WI post-gadolinium images, no. (%) | 7/14 (50%) | 23/33 (70%) | 0.320 |
| Bright spotty lesions, no. (%) | 4/14 (29%) | 18/38 (47%) | 0.344 |
LETM, longitudinally extensive transverse myelitis; NMOSD, neuromyelitis optica spectrum disorder; SSM, short segment myelitis; T1WI, T1-weighted imaging.
*
If more than 1 lesion of the same patient were available, we analysed the axial plane with the largest lesion.