Table 2.
Demographic data from monomicrobial necrotizing fasciitis patients with gram-negative and gram-positive pathogens
| Variable | Gram-negative pathogen (n = 55) | Gram-positive pathogen (n = 45) | P-value |
|---|---|---|---|
| Age (years) | 68.9 ± 12.9 | 64.7 ± 15.4 | 0.107 |
| Gender, male | 37 (67.3) | 32 (71.1) | 0.680 |
| Involved region | |||
| Upper extremities | 23 (41.8) | 17 (37.8) | 0.682 |
| Lower extremities | 32 (58.2) | 28 (62.2) | 0.682 |
| Seawater or seafood contact history | 38 (69.1) | 7 (15.6) | < 0.001* |
| Underlying chronic diseases | |||
| Alcoholism | 15 (27.3) | 12 (26.7) | 0.946 |
| Chronic kidney disease | 18 (32.7) | 7 (15.6) | 0.049* |
| Cerebrovascular disease | 14 (25.5) | 2 (4.4) | 0.004* |
| Chronic liver dysfunction | |||
| HBV | 10 (18.2) | 5 (11.1) | 0.325 |
| HCV | 22 (40.0) | 10 (22.2) | 0.058 |
| HBV or HCV | 29 (52.7) | 15 (33.3) | 0.052 |
| Liver cirrhosis | 17 (30.9) | 10 (22.2) | 0.330 |
| Diabetes Mellitus | 23 (41.8) | 19 (42.2) | 0.968 |
| Gout | 0 (0) | 6 (13.3) | 0.005* |
| Malignancy | 11 (20.0) | 7 (15.6) | 0.565 |
| Peripheral vascular disease | 0 (0) | 2 (4.4) | 0.200 |
Data was presented as mean (standard deviation) or frequency (%)
*: p-value < 0.05