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. 2019 Mar 20;122(5):613–621. doi: 10.1016/j.bja.2019.02.010

Fig. 3.

Fig. 3

Boxplot comparison of flux control ratios (FCR) from MHN (n=36) and MHS (n=23) control and halothane-exposed samples. FCR are generated by internally normalising oxygen flux per muscle mass to the non-halothane-exposed control CI+CII(ETS) (indicated by the horizontal dashed line). Boxplots show median, inter-quartile range (IQR) and min-max range for each phenotype in control and halothane-exposed samples. Statistically significant pairwise comparisons (P<0.05) are labelled with an asterisk (refer to Table 2 for exact P-values). CI, complex I; CII, complex II; CIV, complex IV; ETS, electron transport system; MHN, malignant hyperthermia-negative; MHS, malignant hyperthermia-susceptible; OXPHOS, oxidative phosphorylation.