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. 2019 Mar 20;122(5):613–621. doi: 10.1016/j.bja.2019.02.010

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© 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.

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Fig. 4 — Boxplot comparison showing the change flux control ratios (FCR) (halothane-exposed control) for each respiratory state. MHN samples (n=36) were plotted with MHS samples (n=23), further split into MHS_h (n=12) and MHS_hc (n=11) subgroups. Boxplots show median, inter-quartile range (IQR) and min-max response range for each phenotype. Comparisons labelled with an asterisk show statistically significant post hoc pairwise comparisons (refer to Table 2 for exact P-values). CI, complex I; CII, complex II; CIV, complex IV; ETS, electron transport system; MHN, malignant hyperthermia-negative; MHS, malignant hyperthermia-susceptible; MHS_h, abnormal response in the in vitro contracture test to halothane but not caffeine; MHS_hc, abnormal response in the in vitro contracture test to halothane and caffeine; OXPHOS, oxidative phosphorylation.