Table 1.
Distribution of the DMRs, excluding intergenic regions, and average percentage difference of methylation changes compared to sham at P4 and P24
| Condition | Number of DMRs | Avg % difference of methylation changes | Number of unique genes | Genes with DMRs located on promoter region |
|---|---|---|---|---|
| P4 hypermethylated | 281 | 14.08 ± 4.11 | 240 | ELMOD3, HORMAD2, KRTCAP3, MIR219‐2, MIR290, ODF3, TNS3 |
| P4 hypomethylated | 316 | −13.55 ± 3.68 | 283 | ABCC6, ACVRL1, ADAMTS18, APOBR, ARPP21, CAR13, F2RL3, FXN, GFER, IGBP1B, LAT, LTA, MCEMP1, MPDU1, NKAPL, P2RX1, PF4, SIPA1, SMIM3, TMEM255B, TNFRSF25, ZRSR1 |
| P24 hypermethylated | 380 | 14.74 ± 5.22 | 323 | CCKBR, CDC20, CXCL1, DPYS, EXOSC7, F8A1, FAM217A, FSTL3, HK2, MIR219‐2, MSH4, ODF3, PABPC4, PAQR7, RN5‐8S, SALL3, SGK2, SIPA1, STK3, TENM3, UPB1 |
| P24 hypomethylated | 246 | −14.42 ± 4.53 | 219 | ALOX12E, CD55, COX6A2, DOK3, MIR671, ODF3, OTOP3, RMND1, SLAMF8, SNCG, SOAT2, ST13, TRIM17 |