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. 2019 Aug 6;60(1):96–106. doi: 10.1002/jcph.1504

Table 1.

Definitions of Metabolism Profiles Assigned to Study Participants on CYP2D6 Genotyping

Metabolism Classification Definitions
Poor metabolizers Participants carrying 2 inactive CYP2D6 alleles, CYP2D6*3, *4, *5, *6, *7, *8, *11, *12, *14, *15, *19, *20, and *36
Intermediate metabolizers Participants carrying 1 inactive and 1 active CYP2D6 allele (CYP2D6*1, *2, *2A, and *35) or 2 partially active alleles (CYP2D6*9, *10, *17, *29, and *41)
Extensive metabolizers Participants carrying 2 active alleles or 1 active and 1 partially active allele
Ultrarapid metabolizers Participants carrying 3 or more active alleles

CYP, cytochrome P450.