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. 2020 Jan 16;12:363–373. doi: 10.2147/CMAR.S230171

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© 2020 Chen et al.

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Direct interaction of LINC01783 with miR-199b-5p. (A) Cytoplasmic and nuclear level of LINC01783 in HeLa and C-33A cells as determined by qRT-PCR. (B) MiR-199b-5p expression in cervical cancer cell lines (SW756, C-33A, SiHa, HeLa and CaSki) and normal human cervical epithelial cell line HcerEpic as indicated by qRT-PCR. (C) MiR-199b-5p expression in cervical cancer tissues and normal tissues on TCGA dataset. (D) The correlation between miR-199b-5p and LINC01783 on TCGA dataset. (E) Bioinformatics evidences of miR-199b-5p binding onto 3ʹ-UTR of LINC01783. (F) Dual-luciferase reporter gene assay in HeLa and C-33A cells post transfection with miR-NC or miR-199b-5p mimics. (G) Amount of LINC01783 and miR-199b-5p in HeLa and C-33A cells as detected by RIP experiments. *P<0.05, **P<0.01, ***P<0.001.