Table 3.
Potential impact of combined screening strategies for anomalies with antenatal detection rate <85%
| Live born | Antenatal diagnosis | Pre‐discharge diagnosis | Missed diagnoses | Sensitivity: pulse oximetry a | Potential additional pre‐discharge diagnoses with pulse oximetry | Detection with combined strategies | |
|---|---|---|---|---|---|---|---|
| d‐TGA | 67 | 40 (60) | 17 (25) | 10 (15) | 92% | 9 | 66 (98) |
| AAO | 44 | 17 (39) | 12 (27) | 15 (34) | 36% | 5 | 34 (77) |
| TAPVD | 7 | 2 (29) | 3 (43) | 2 (28) | 91% | 2 | 7 (100) |
| Valvular stenosis | 13 | 5 (38) | 8 (62) | ‐ | ‐ | ‐ | 13 (100) |
Abbreviations: AAO, aortic arch obstruction; d‐TGA, d‐loop transposition of the great arteries; TAPVD, total anomalous pulmonary venous drainage.
a
Prudhoe et al12. – anomaly specific sensitivity derived from 13 studies involving 258 809 participants.