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. 2020 Jan 21;10:854. doi: 10.1038/s41598-020-57817-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Chromosome segregation error does not affect the result of blastocyst transfer. (a) Photograph of the result of cesarean section. The eye color was used to determine if an observed embryo was obtained. (b) Cumulative bar plot showing the relationship between born/abort ratio and most severe chromosome segregation error by 3^rd mitosis. (c) Cumulative bar plot showing the relationship between severity of chromosome segregation error during 1^st, 2^nd, and 3^rd mitosis and born/abort ratio. (d) Snapshot of “Born” case embryo showing micronuclei (arrowhead) at 1^st mitosis. Bar = 50 µm. (e) Photograph of a pup from embryo showing micronuclei at 1^st mitosis.