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. 2020 Jan 21;10:777. doi: 10.1038/s41598-019-57275-0

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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The survival analyses of mice with and without gut-leakage induced by dextran sulfate solution (DSS) in drinking water or control water of wild-type (WT), FcGRIIb−/− and pristane mice (A) (n = 10 per group) and time course of gut-leakage as measured by FITC-dextran assay of DSS mice (B) and mice in the protocol of co-housing (plus fecal gavage) with 40-wk-old WT (WT/ feces WT) or 40-wk-old FcGRIIb−/− (WT/feces FcGRIIb−/−) (C) (n = 6–9 per time-point) were demonstrated. In addition, time-course of serum anti-dsDNA Ig in mice with DSS or the co-housing (plus fecal gavage) in WT, FcGRIIb−/− and pristane mice (D–F) (n = 6–9 per time-point) were demonstrated.