Table 1.
Inhibitory effect of AFE on α‐amylase, α‐glucosidase, and DPP‐4
| Inhibition (%) | ||||
|---|---|---|---|---|
| α‐Amylase | ||||
| AFE (μg mL−1) | Porcine pancreas | Human saliva | α‐Glucosidase | DPP‐4 |
| 7.8 | 8.68 ± 1.1 | 7.58 ± 1.62 | 1.08 ± 0.29 | ND |
| 15.6 | 22.09 ± 1.87 | 24.1 ± 1.23 | 3.15 ± 0.95 | ND |
| 31.3 | 33.71 ± 1.59 | 26.54 ± 1.92 | 5.15 ± 1.14 | ND |
| 62.5 | 42.78 ± 1.24 | 40.5 ± 1.34 | 7.58 ± 1.69 | 1.26 ± 0.56 |
| 125 | 44.95 ± 1.57 | 51.24 ± 1.61 | 16.03 ± 1.82 | 2.15 ± 0.62 |
| 250 | 50.56 ± 1.98 | 65.41 ± 1.68 | 22.64 ± 1.57 | 3.41 ± 0.56 |
| 500 | 71.26 ± 1.25 | 75.24 ± 1.35 | 30.23 ± 1.98 | 9.04 ± 0.93 |
| 1000 | 84.15 ± 1.63 | 89.14 ± 1.56 | 93.92 ± 1.21 | 11.87 ± 1.08 |
| 2000 | ND | ND | ND | 27.9 ± 1.4 |
| 4000 | ND | ND | ND | 53.21 ± 4.21 |
| IC50 (μg mL−1) | ||||
| AFE | 135.70 | 106.70 | 562.9 | 3770 |
| Acarbose | 25 | 24.2 | 75 | |
| Diprotin A | 10 | |||
ND, not done.
Values are average mean of triplicates performed on two different occasions and presented as IC50 values.