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Fast and slow responders in chemoprophylaxis with sporozoite (CPS) immunization. Six CPS immunization studies comprising 67 homologously challenged volunteers were studied for the presence of fast and slow responders. Forty‐seven volunteers (60%) were PCR‐negative for the presence of parasites at the second immunization and were classified as fast responders. Of these, 37 (92.5%) were fully protected upon challenge. Only 15 slow responders (55%) were fully protected upon challenge
