Table 3.
Meta‐analysis of difference* in 48‐week change in ambulatory function between deflazacort and prednisone/prednisolone groups
| Pooled estimate | SE | 95% CI | P value | Cochran Q | I 2 (%) | |
|---|---|---|---|---|---|---|
| 6MWD (meters) | 28.3 | 11.5 | (5.7, –50.9) | 0.01 | 0.09 | 0.00 |
| 4‐stair climb (seconds) | −2.3 | 0.9 | (−4.1, −0.5) | 0.01 | 0.54 | 0.00 |
| Rise from supine (seconds) | −2.9 | 1.0 | (−4.9, −0.9) | <0.01 | 0.13 | 0.00 |
| 10‐meter walk/run (seconds) | 0.2 | 0.8 | (−1.4, 1.8) | 0.85 | 0.18 | 0.00 |
| NSAA total score | 1.2 | 0.6 | (−0.01, 2.3) | 0.05 | 0.01 | 0.00 |
| NSAA linearized score | 2.9 | 1.5 | (0.1, 5.8) | 0.04 | 0.14 | 0.00 |
Abbreviations: 6MWD, 6‐minute walk distance; CI, confidence interval; NSAA, North Star Ambulatory Assessment; SE, standard error.
*
Difference calculated as deflazacort − prednisone.