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. 2020 Jan 10;12(1):1709322. doi: 10.1080/19420862.2019.1709322

Table 6.

Functional profile of BI 655088 and BI 655089.

Assay BI 655088 BI 655089
hFractalkine Competition IC50 (nM) 0.4 0.7
Chemotaxis IC50 (nM) 2.7 3.0
Ligand Internalization IC50 (nM) 0.33 0.37
Calcium Influx IC50 (nM) 1.3 3.2