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A model for coordinate regulation of rpoS by ArcZ-CyaR interactions. (A) ArcZ up-regulates rpoS expression by different mechanisms: (i) base-pairing with the 5ʹ UTR of rpoS to open up an inhibitory hairpin; and (ii) repression of CyaR-dependent rpoS degradation. (B) Mechanism of CyaR regulation by ArcZ. ArcZ base-pairs with CyaR and degrades CyaR through RNase E.
