Table 1. Baseline input values used for cost-saving analyses.
Parameter | Baseline value | Reference |
---|---|---|
Direct medical cost for screening ($) | ||
Quantitative method | 17.76 | |
Semi-quantitative method | 0.86 | |
Direct nonmedical cost ($) | ||
Transportation | 9.265 | |
Indirect medical costs for healthcare ($) | ||
End-stage renal disease | 13,149.62 | HIRA annual report |
Cardiovascular disease | 25,634.48 | HIRA annual report |
All-cause mortality | 6,810.38 | HIRA annual report |
Incidences of clinical outcomes, normo-albuminuria (per year) | ||
End-stage renal disease | 0.0154 | Ref 14 |
Cardiovascular disease | 0.0095 | Ref 14 |
All-cause mortality | 0.0006 | Ref 13 |
Relative hazards of clinical outcomes, albuminuria versus normo-albuminuria* | ||
End-stage renal disease | 3.432 (95% CI, 2.757–4.271) | Fig 2 |
Cardiovascular disease | 1.315 (95% CI, 1.250–1.384) | Fig 2 |
All-cause mortality | 1.480 (95% CI, 1.408–1.556) | Fig 2 |
Probabilities (distribution) | ||
Negative at quantitative screening | Beta (917, 193)** | Table 2 |
Negative at semi-quantitative screening | Beta (615, 495)** | Table 2 |
False negative among the negative population at SemiQ screening | Beta (36, 579)** | Table 2 |
True positive at Q test confirmation among the positive population at SemiQ test screening | Beta (157, 338)** | Table 2 |
* These values were used to estimate incidences of clinical outcomes among participants with albuminuria.
** Beta distribution.