Table 2. Comparison of integration sites in 293mCAT cells of MLV IN XN and MLV IN TP- derived from TP-16 tumor.
Sample | Unique sites | TSS+/-1kb (%) | CpG+/- 1kb (%) |
---|---|---|---|
WTa | 64828 | 14208 (21.9) | 18864 (29.1) |
IN XNa | 37638 | 2029 (5.4) | 3171 (8.4) |
IN TP-16b | 47093 | 2959 (6.3) | 4541 (9.6) |
RICc | 10000 | 169 (1.7) | 270 (2.7) |
a Viral spread through plasmid transfection of 293mCAT cells
b Viral spread by infection of viruses extracted from mouse tumor
cRIC, random integration control