Fig. 4.

Sensitivity analysis according to the modifiers. (A) PPI and dicumarinics-related upper GIB, excluding the study by Massó González EL et al. (B) H2RA and dicumarinics-related upper GIB, excluding the study by Massó González EL et al. The size of each square is proportional to the study’s weight. The diamond indicates the summary estimate from the pooled studies (random effect model).

PPI, proton-pump inhibitor; GIB, gastrointestinal bleeding; H2RA, histamin-2 receptor antagonist; CI, confidence interval.