Table 1. Changes in palms, footpads, ankles of forelimbs and hindlimbs after induction of arthritis.

			Study groups
	Normal control group			CIA group
	Baseline	After 2 weeks		Baseline	After 2 weeks
	Mean±SD	Mean±SD	p	Mean±SD	Mean±SD	p
Right palm	2.1±0.1	2.3±0.2	0,35	2.5±0.2	2.8±0.2	0.013*
Left palm	2.1±0.1	2.3±0.2	0,12	2.5±0.2	3.2±0.3	0.015*
Right footpad	3.0±0.0	3.2±0.1	0,12	3.7±0.1	5.8±0.4	0.001†
Left footpad	3.1±0.1	3.2±0.1	0,44	3.9±0.2	5.7±0.4	0.004*
Ankle thickness of right forelimb	3.7±0.3	3.7±0.4	0,54	3.7±0.4	4.2±0.5	0.001†
Ankle thickness of left forelimb	3.7±0.4	3.7±0.3	0,26	3.7±0.4	4.2±0.5	0.001†
Ankle thickness of right hindlimb	5.9±0.7	6.1±0.7	0,46	5.6±0.7	7.6±1.4	0.001†
Ankle thickness of left hindlimb	5.8±0.7	6.1±1.2	0,45	5.7±0.6	7.7±1.4	0.001†
CIA: Collagen-induced arthritis; SD: Standard deviation; * p<0.05; † p<0.001.