Skip to main content
. Author manuscript; available in PMC: 2020 Jul 7.
Published in final edited form as: Nat Genet. 2020 Jan 7;52(1):56–73. doi: 10.1038/s41588-019-0537-1

Figure 5. Predicted target genes by phenotype and significantly enriched pathways.

Figure 5

(a) Venn diagram showing the associated phenotype (ER-positive, ER-negative, ER-neutral) for the Level 1 target genes, predicted by the CCVs and HPPVs. * ER-positive or ER-negative target genes also targeted by ER-neutral signals. (b) Heatmap showing clustering of pathway themes over-represented by INQUISIT Level 1 target genes. Color represents the relative number of genes per phenotype within enriched pathways, grouped by common themes. ER-positive, ER-negative, ER-neutral, and all phenotypes together (strong).