Table 3.
Differences of Clinical Characteristics Between A+B+ and A−B+ C. difficile with Resistance to MLSB
| Characteristicsa | NO. (%) of Diarrheal Patients | Analysis Results | ||||||
|---|---|---|---|---|---|---|---|---|
| Patients with C. difficile Isolates with Resistance to MLSB | Bivariate | Multivariate Logistic | ||||||
| A+B+ (n=90) | A−B+ (n=88) | OR | 95%Cl | P value | OR | 95%Cl | P value | |
| Gender, male | 48(53.3%) | 51(58.0%) | 1.21 | 0.67–2.18 | 0.535 | |||
| Years of age, >55 | 46(51.1%) | 48(54.6%) | 1.15 | 0.64–2.07 | 0.646 | |||
| CDI severity score, >2 (n=54) | 14(15.6%) | 40(45.5%) | 4.52 | 2.23–9.18 | <0.001 | 7.43 | 2.31–23.87 | 0.001 |
| Stool | ||||||||
| S-RBC Positive (n=9) | 5 (5.6%) | 4 (4.6%) | 0.81 | 0.21–3.12 | 0.759 | |||
| S-WBC Positive (n=39) | 22 (24.4%) | 17 (19.3%) | 0.74 | 0.36–1.51 | 0.409 | |||
| OB Positive (n=43) | 20 (22.2%) | 23 (26.1%) | 1.24 | 0.62–2.46 | 0.542 | |||
| Blood | ||||||||
| CRP (mg/L) >10 (n=82) | 38 (42.2%) | 44(50.0%) | 0.73 | 0.41–1.32 | 0.298 | |||
| WBC (cells ×109/L) >10 (n=50) | 18 (20.0%) | 32 (36.4%) | 2.29 | 1.16–4.49 | 0.016 | 0.58 | 0.18–1.89 | 0.368 |
| Neutrophils > 70% (n=79) | 34 (37.8%) | 45(48.9%) | 0.64 | 0.35–1.15 | 0.136 | |||
| Lymphocyte > 40% (n=139) | 23 (25.6%) | 16 (18.2%) | 1.55 | 0.75–3.17 | 0.236 | |||
| Monocyte > 10% (n=20) | 10 (11.1%) | 10 (11.4%) | 0.88 | 0.34–2.28 | 0.788 | |||
| Eosinophils > 8% (n=6) | 2 (2.2%) | 4 (4.5%) | 2.10 | 0.37–11.74 | 0.400 | |||
| Basophils > 1% (n=1) | 1 (1.1%) | 0 | N/Ab | N/A | N/A | |||
| Hb (g/L) < 120 (n=95) | 45 (50.00%) | 50 (56.8%) | 0.76 | 0.42–1.37 | 0.362 | |||
| PLT (cells ×109/L) <100 (n=19) | 4 (4.4%) | 15 (17.0%) | 4.42 | 1.40–13.90 | 0.011 | 5.19 | 1.58–17.04 | 0.007 |
| Creatinine (umol/L) > 111 (n=20) | 9 (10.0%) | 11 (12.5%) | 0.78 | 0.31–1.98 | 0.598 | |||
| Glucose (mmol/L) >6.1 (n=40) | 22 (24.4%) | 18 (20.5%) | 1.26 | 0.62–2.55 | 0.524 | |||
| Kalium (mmol/L) >5.5 (n=5) | 1 (1.1%) | 4 (4.5%) | 0.47 | 0.04–5.30 | 0.543 | |||
Notes: aS-RBC: stool-red blood cell; S-WBC: stool-white blood cell; OB: occult blood; CRP: C-reactive protein; Hb: haemoglobin; PLT: platelets. bN/A: not applicable.