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. 2020 Jan 21;40(1):BSR20191900. doi: 10.1042/BSR20191900

Figure 2. LINC00152 activates Wnt/β-catenin pathway and regulates nuclear translocation of β-catenin.

Figure 2

(A) The effect of LINC00152 on the Wnt/β-catenin pathway proteins (β-catenin, c-myc as well as cyclin D1) was assessed by Western blotting. (B) Nuclear translocation of β-catenin was detected in RA FLS after LINC00152 was overexpressed or silenced. (C and D) Proliferative ability RA FLS transfected with sh-LINC00152 or pcDNA-LINC00152 was measured after treatment with LiCl or DKK1 over expression vector. (E) Apoptosis in RA FLS was detected after treatment with indicated plasmids; *P < 0.05, **P < 0.01.