Figure 4.
In vivo recovery of human platelets (PLTs) in SCID mice. PLTs were treated with 10 mWcm−2 405 nm light for 8 h before transfusion into SCID mice. The % of initial recovery of non-treated (n = 14 ± SEM) and light-treated (n = 12 ± SEM) PLTs was monitored over time, up to 24 h. Negligible amounts of human PLTs were consistently observed at 24 h in all treatments, therefore only data up to 10 h were analyzed for significance. Results demonstrated no significant difference [P > 0.05; two sample t test (Minitab v18)] between the light-treated and non-light treated (control) PLTs.