Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jan 15;11:368. doi: 10.3389/fnagi.2019.00368

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Adler, Chiang, Mayne, Ning, Zhang, Xu, Cheng and Figeys.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Aging disrupts the circadian regulation of proteins involved in energy metabolism in the hippocampus. (A) Schematic depiction of proteins involved in energy metabolism, including glycolysis, pyruvate metabolism, the TCA cycle, and oxidative phosphorylation. Proteins that displayed loss or gain of circadian rhythmicity in abundance during aging are highlighted in color. Proteins that were reliably quantified, but not detected as circadian at either age, are shown in gray. (B) Temporal abundance profiles of rhythmic proteins identified in young mice involved in energy metabolism.