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Bacteriostatic activity of IMB-0283 in BALB/C mice. DCS, IMB-0283, and INH were each administered at 25 mg/kg 15 times, and the vehicle CMC-Na was used as a negative control. INH and IMB-0283 reduces the bacterial load in lungs from 5.58 to 3.29 or 4.40 (log CFU/mL), respectively, but DCS showed no antibacterial activity (P > 0.5). ****Statistically significant difference from the negative control (P < 0.0001; n = 6).
