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. 2020 Jan 15;7:925. doi: 10.3389/fchem.2019.00925

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Copyright © 2020 Takezawa and Shionoya.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Schematic representation of metal-triggered structural transformation between DNA duplexes and three-way junctions (3WJs). (B) Sequences of the DNA strands used for the metal-triggered structural conversion. (C) Native polyacrylamide gel electrophoresis (PAGE) analysis of the mixture of DNA strands in the absence and in the presence of one equivalent of Ni^II ions. “+EDTA” indicates the result after the removal of Ni^II ions by EDTA. Adapted from a literature (Takezawa et al., 2016) published by The Royal Society of Chemistry under the Creative Commons CCBY license.