FIG 2.

CCA ordinations for functional composition of the microbiome, behavioral dysregulation, and caregiver behavior covariates. Only covariates that have significant main effects or are part of a significant interaction are depicted in each ordination. Significance was assessed using PERMANOVA (α = 0.05). See Tables S2c and d for statistical results. (A) Ordination of functional (KO level) composition. Each point represents a sample and is colored by the participant’s impulsivity score. (B) Ordination of functional (KO level) composition; sample locations are identical to panel A. In this panel, the outer circle of the point is colored according to the sample’s inhibitory control score, and the inner circle is shaded from white to black indicating the sample’s parent-child dysfunction score. (C) Ordination of functional (KO level) composition; sample locations are identical to panels A and B. The color of the outer circle corresponds to the sample’s depressive problems score, and the inner circle is shaded identically to panel B.