Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Impact of heme on tumor microenvironment. Other than sustaining cancer cells growth (1), heme could also potentially affect other processes within the microenvironment, including macrophage polarization (2), the angiogenic potential of tumor endothelial cells (3), matrix remodeling by cancer-associated fibroblasts (4), and nerve-cancer cross-talk (5).
