Table I.

Baseline patient characteristics

	Patient 1	Patient 2
Age	26	24
Gender	M	F
Employment status	On disability	On disability
Hurley stage	III	III
Anatomic region	Bilateral axillae, abdomen, bilateral inguinal folds	Inframammary, abdominal pannus, bilateral inguinal folds, perineum, buttocks, intergluteal cleft, posterior thighs
Appearance	>10 draining abscesses and ulcerations	10-20 ulcerations
Comorbidities	Anemia of chronic disease, depression, Obesity, paradoxical psoriasis	Anemia of chronic disease, diabetes mellitus type II, endometriosis, gastroesophageal reflux disorder, hypothyroidism, migraines, morbid obesity, osteoporosis, Polycystic ovarian syndrome, pyoderma gangrenosum
HS maintenance regimen	Tofactinib 5 mg 2x daily; amoxicillin 500 mg 2x daily; cyclosporine 300 mg (∼5 mg/kg) daily	Tofacitinib 5 mg 2× daily; 4 week antibiotic cycle of amoxicillin + amoxicllin-clavulanate ×3 weeks and azithromycin ×1 week; 1250 mg MMF 2× daily; triamcinolone ointment
Prior therapies	Adalimumab, infliximab, methotrexate, oral amoxicillin, oral amoxicillin-clavulanate, oral doxycycline, oral minocycline, acitretin	Adalimumab, etanercept, infliximab, ustekinumab, anakinra, azathioprine, cyclosporine, methotrexate, oral steroids, tacrolimus, oral contraceptive pills