Figure 2.

PBMT improves spatial learning and memory of APP/PS1 mice in the MWM. (a) Representative swimming traces on day 5 during the place navigation trial showing the effects of PBMT on the spatial memory of WT and APP/PS1 mice. (b) The escape latency of mice to find the hidden platform was recorded on each training day. (c) Mean distance per day for path length was shown during acquisition of the hidden platform task. (d) Representative swimming traces of the four groups of mice exhibited after the training trial. (e) The number of crossing the platform during a 60‐s probe trial of MWM test. (f) Percentage of time spent in target quadrant of the original platform position. All the data are reported as mean ± SEM. n = 9 animals per group. *p < 0.05 and **p < 0.01 versus the WT group; #p < 0.05 and ##p < 0.01 versus the APP/PS1 group