Fig. 5.

Effects of CMT on the nodal graph theory characteristics of structural and functional connectivity networks. (A) effects of CMT on the DTI structural connectivity network, (B) effects of CMT on the clustering coefficient of the functional connectivity network, (C) effects of CMT on the betweenness centrality of the functional connectivity network. In each sub-plot, nodal characteristics are plotted (left axis) as a function of network density, while the right axis shows the T statistic of the multivariate analysis of group differences. Network costs at which significant CMT-control differences appear are marked with segmented line and dot (p < 0.05, FDR-corrected across network nodes). Blue lines: mean values, control group, red lines: mean values, CMT group, transparent area reflects the variability of measurements (± 1SD range). The right panels in each sub-plot shows the CGA dependency of the main effect. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)