Table. 1.
(A)Whole hippocampal and (B) Subfield LME analysis. Significant p-values are shown in bold, individual intervention analysis shows FDR corrected p-values.
| A | Left | Right | ||||
|---|---|---|---|---|---|---|
| Long-term effect | Fvalue | p value | DF | F value | p value | DF |
| RES | 3.60 | 0.060 | 159.2 | 0.19 | 0.663 | 159.9 |
| COG | 1.53 | 0.219 | 158.8 | 0.71 | 0.401 | 159.5 |
| PRT+CCT vs SHAM+SHAM | 5.10 | 0.041 | 83.8 | 0.77 | 0.650 | 84.0 |
| PRT+SHAM vs SHAM+SHAM | 7.22 | 0.027 | 79.6 | 0.62 | 0.650 | 79.9 |
| CCT+SHAM vs SHAM+SHAM | 2.70 | 0.104 | 84.7 | 0.18 | 0.650 | 85.0 |
| B | PRT+CCT vs SHAM+SHAM | PRT+SHAM vs SHAM+SHAM | ||||
| F value | p value | DF | F value | p value | DF | |
| Subiculum | 0.74 | 0.392 | 83.6 | 7.14 | 0.023 | 80.2 |
| CA1 | 2.85 | 0.119 | 84.6 | 8.81 | 0.020 | 81.0 |
| Dentate gyrus | 6.05 | 0.075 | 83.5 | 5.53 | 0.035 | 79.1 |
| CA4 | 4.67 | 0.083 | 83.7 | 3.39 | 0.086 | 79.6 |
| Presubiculum | 2.87 | 0.119 | 83.7 | 0.59 | 0.442 | 80.9 |
RES = PRT+CCT and PRT+SHAM vs CCT+SHAM and SHAM+SHAM.
COG = PRT+CCT and CCT+SHAM vs PRT+SHAM and SHAM+SHAM.
PRT = progressive resistance training.
CCT = computerised cognitive training.