Table 2. ORs and 95% CIs for the subtypes of ischemic stroke according to GGT based on multinomial logistic regression.
| GGT quartile | Q1 | Q2 | Q3 | Q4 | p for trend |
|---|---|---|---|---|---|
| CE (reference=SVO) | |||||
| Unadjusted | 1 | 1.50 (0.83–2.71) | 2.24 (1.18–4.23) | 2.68 (1.43–5.02) | 0.001 |
| Model 1* | 1 | 1.50 (0.82–2.73) | 2.43 (1.27–4.62) | 3.00 (1.58–5.70) | <0.001 |
| Model 2† | 1 | 1.61 (0.84–3.06) | 2.79 (1.37–5.70) | 3.42 (1.59–7.37) | <0.001 |
| Model 2+AF | 1 | 1.52 (0.75–3.08) | 2.37 (1.10–5.10) | 2.60 (1.14–5.96) | 0.01 |
| LAA (reference=SVO) | |||||
| Unadjusted | 1 | 0.85 (0.49–1.47) | 1.42 (0.79–2.56) | 1.10 (0.60–2.00) | 0.38 |
| Model 1 | 1 | 0.87 (0.50–1.51) | 1.47 (0.81–2.66) | 1.16 (0.63–2.13) | 0.29 |
| Model 2 | 1 | 0.81 (0.46–1.43) | 1.36 (0.72–2.58) | 1.10 (0.54–2.23) | 0.45 |
| UD (reference=SVO) | |||||
| Unadjusted | 1 | 0.73 (0.39–1.37) | 1.11 (0.57–2.17) | 1.29 (0.67–2.49) | 0.26 |
| Model 1 | 1 | 0.74 (0.39–1.38) | 1.10 (0.56–2.15) | 1.27 (0.65–2.46) | 0.29 |
| Model 2 | 1 | 0.73 (0.38–1.42) | 1.10 (0.53–2.29) | 1.25 (0.57–2.75) | 0.39 |
Data are OR (95% CI) values.
*Adjusted for sex and age, †Adjusted for sex, age, body mass index, systolic blood pressure, fasting blood glucose, total cholesterol, aspartate aminotransferase, alanine aminotransferase, previous stroke, hypertension, diabetes, hyperlipidemia, liver disease, and smoking.
AF: atrial fibrillation, CE: cardioembolism, GGT: gamma-glutamyl transferase, LAA: large-artery atherosclerosis, OR: odds ratio, SVO: small-vessel occlusion, UD: undetermined.