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. 2019 Oct 15;40:100719. doi: 10.1016/j.dcn.2019.100719

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© 2019 The Authors. Published by Elsevier Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — Brain areas showing differences in activation for trained versus novel problems. (a) Trained problems elicited greater activity than novel problems (shown in red-yellow) in the hippocampus (HIP), parahippocampal gyrus (PHG), angular gyrus (AG), middle temporal gyrus (MTG), medial prefrontal cortex (mPFC) and posterior cingulate cortex (PCC). Novel problems elicited greater activity (shown in blue-green) in the inferior frontal gyrus (IFG), insula, middle and superior frontal gyri, intraparietal sulcus (IPS), supramarginal gyrus (SMG), supplementary motor area (SMA), middle occipital gyrus (MOG), cerebellum (CBL), and the caudate (CAU). (b) Medial temporal lobe (MTL) activation clusters (shown in orange) overlaid on anterior (a) and medial (m) HIP (cyan) and PHG (green) anatomical boundaries from the AAL atlas. L: left; R: right.