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. 2019 Dec 10;8(4):CNS47. doi: 10.2217/cns-2019-0017

Table 1. . Patient characteristics by treatment regimen.

Patient characteristics All patients Chemotherapy and radiotherapy Chemotherapy only Radiotherapy only Supportive treatment
Number 210 67 (31.9) 16 (7.6) 23 (11.0) 104 (49.5)
Mean age (SD) 74.2 (6.29) 69.8 (4.0) 72.5 (6.1) 72.5 (6.0) 76.8 (6.0)
Age group (years):
  – 65–<70
  – 70–<75
  – 75+

71 (33.8)
50 (23.8)
89 (42.4)

40 (59.7)
18 (26.9)
9 (13.4)

7 (43.8)
2 (12.5)
7 (43.8)

10 (43.5)
6 (26.1)
7 (30.4)

14 (13.5)
24 (23.1)
66 (63.5)
Sex:
  – Men
  – Women

118 (56.2)
92 (43.8)

35 (52.2)
32 (47.8)

8 (50.0)
8 (50.0)

14 (60.9)
9 (39.1)

61 (58.7)
43 (41.3)
Performance status:
  – 0
  – 1
  – 2
  – 3+
  – Unknown

23 (11.0)
73 (34.8)
41 (19.5)
61 (29.0)
12 (5.7)

17 (25.4)
31 (46.3)
9 (13.4)
5 (7.5)
5 (7.5)

1 (6.3)
12 (75.0)
2 (12.5)
1 (6.3)
0 (0.0)

2 (8.7)
9 (39.1)
7 (30.4)
3 (13.0)
2 (8.7)

3 (2.9)
21 (20.2)
23 (22.1)
52 (50.0)
5 (4.8)
Treatment center:
  – Glasgow
  – Brighton
  – Manchester

100 (47.6)
37 (17.6)
73 (34.8)

16 (23.9)
9 (13.4)
42 (62.7)

16 (100.0)
0 (0.0)
0 (0.0)

3 (13.0)
6 (26.1)
14 (60.9)

65 (62.5)
22 (21.2)
17 (16.3)
MGMT promoter methylation:
  – Tested
  – Methylated
  – Unmethylated
  – Failed testing

80
25 (31.3)
50 (62.5)
5 (6.3)

32
9 (28.1)
23 (71.9)
2 (6.3)

16
10 (62.5)
6 (37.5)
0 (0.0)

9
2 (22.2)
6 (66.7)
1 (11.1)

21
4 (19.0)
15 (71.4)
2 (9.5)
Neurosurgery:
  – Stereotactic biopsy
  – Subtotal resection <90%
  – Gross total resection >90%
  – Unknown surgery
  – No surgery

30 (14.3)
58 (27.6)
37 (17.6)
1 (4.8)
84 (40.0)

7 (10.4)
42 (62.7)
18 (26.9)
0 (0.0)
0 (0.0)

7 (43.8)
4 (25.0)
4 (25.0)
1 (6.3)
0 (0.0)

6 (26.1)
4 (17.4)
6 (26.1)
0 (0.0)
7 (30.4)

10 (9.6)
8 (7.7)
9 (8.7)
0 (0.0)
77 (74.0)
Diagnosis:
  – Pathological diagnosis
  – Radiological diagnosis

122 (58.1)
88 (41.9)

67 (100.0)
0 (0.0)

16 (100.0)
0 (0.0)

16 (69.6)
7 (30.4)

23 (22.1)
81 (77.9)

The numbers in brackets represent percentages unless indicated otherwise.

SD: Standard deviation.