Table 1. . Patient characteristics by treatment regimen.
Patient characteristics | All patients | Chemotherapy and radiotherapy | Chemotherapy only | Radiotherapy only | Supportive treatment |
---|---|---|---|---|---|
Number | 210 | 67 (31.9) | 16 (7.6) | 23 (11.0) | 104 (49.5) |
Mean age (SD) | 74.2 (6.29) | 69.8 (4.0) | 72.5 (6.1) | 72.5 (6.0) | 76.8 (6.0) |
Age group (years): – 65–<70 – 70–<75 – 75+ |
71 (33.8) 50 (23.8) 89 (42.4) |
40 (59.7) 18 (26.9) 9 (13.4) |
7 (43.8) 2 (12.5) 7 (43.8) |
10 (43.5) 6 (26.1) 7 (30.4) |
14 (13.5) 24 (23.1) 66 (63.5) |
Sex: – Men – Women |
118 (56.2) 92 (43.8) |
35 (52.2) 32 (47.8) |
8 (50.0) 8 (50.0) |
14 (60.9) 9 (39.1) |
61 (58.7) 43 (41.3) |
Performance status: – 0 – 1 – 2 – 3+ – Unknown |
23 (11.0) 73 (34.8) 41 (19.5) 61 (29.0) 12 (5.7) |
17 (25.4) 31 (46.3) 9 (13.4) 5 (7.5) 5 (7.5) |
1 (6.3) 12 (75.0) 2 (12.5) 1 (6.3) 0 (0.0) |
2 (8.7) 9 (39.1) 7 (30.4) 3 (13.0) 2 (8.7) |
3 (2.9) 21 (20.2) 23 (22.1) 52 (50.0) 5 (4.8) |
Treatment center: – Glasgow – Brighton – Manchester |
100 (47.6) 37 (17.6) 73 (34.8) |
16 (23.9) 9 (13.4) 42 (62.7) |
16 (100.0) 0 (0.0) 0 (0.0) |
3 (13.0) 6 (26.1) 14 (60.9) |
65 (62.5) 22 (21.2) 17 (16.3) |
MGMT promoter methylation: – Tested – Methylated – Unmethylated – Failed testing |
80 25 (31.3) 50 (62.5) 5 (6.3) |
32 9 (28.1) 23 (71.9) 2 (6.3) |
16 10 (62.5) 6 (37.5) 0 (0.0) |
9 2 (22.2) 6 (66.7) 1 (11.1) |
21 4 (19.0) 15 (71.4) 2 (9.5) |
Neurosurgery: – Stereotactic biopsy – Subtotal resection <90% – Gross total resection >90% – Unknown surgery – No surgery |
30 (14.3) 58 (27.6) 37 (17.6) 1 (4.8) 84 (40.0) |
7 (10.4) 42 (62.7) 18 (26.9) 0 (0.0) 0 (0.0) |
7 (43.8) 4 (25.0) 4 (25.0) 1 (6.3) 0 (0.0) |
6 (26.1) 4 (17.4) 6 (26.1) 0 (0.0) 7 (30.4) |
10 (9.6) 8 (7.7) 9 (8.7) 0 (0.0) 77 (74.0) |
Diagnosis: – Pathological diagnosis – Radiological diagnosis |
122 (58.1) 88 (41.9) |
67 (100.0) 0 (0.0) |
16 (100.0) 0 (0.0) |
16 (69.6) 7 (30.4) |
23 (22.1) 81 (77.9) |
The numbers in brackets represent percentages unless indicated otherwise.
SD: Standard deviation.