Table 1.
Clinical characteristicsa) of the patient population at admissionb)
| HIV only | Malaria only | Malaria and HIV | |
|---|---|---|---|
| N | 58 | 61 | 70 |
| Age, years | 39 (22–84) | 40 (18–79) | 40 (20–65) |
| Sex, females (%) | 50 (29/58) | 41 (25/61) | 50 (35/70) |
| Hemoglobin (g/dL) | 8.9 (2.9–15.2) | 11.2 (3.2–17.0) | 9.4 (2.5–15.7) |
| Leukocytes (× 109/L) | 8.2 (0.3–25.4) | 6.9 (1.3–15.5) | 7.8 (0.9–21.8) |
| Platelets (×109/L) | 220 (13–682) | 124 (11–452) | 90 (8–330) |
| Se-Creatinine (μmol/L) | 161 (41–873) | 127 (57–357) | 223 (62–1529) |
| Se-Glucose (mmol/L) | 6.1 (3.3–10.6) | 8.7 (3.6–40.5) | 6.12 (1.5–27.0) |
| Liver failure (%)c) | 5 (4/57) | 5 (3/61) | 17 (12/70) |
| Coagulation disturb. (%)d) | 0 | 2 (1/61) | 13 (9/70) |
| Cerebral affection (%) e) | 33 (19/58) | 25 (15/61) | 31 (22/70) |
| Systolic blood pressure | 115 (90–160) | 122 (70–240) | 115 (80–170) |
| Respiratory rate | 29 (12–56) | 22 (12–68) | 24 (16–42) |
| CD4 T-cells (106/l)f) | 120 (10–196) | 0 | 221 (14–632) |
| HIV-RNA (copies/ml) | 2.6 × 104 (0–5.1 × 105) | 0 | 4.2 × 104 (0–8.3 × 105) |
| ART before admission | 29 (17/58) | 0 | 19 (13/70) |
| Effective ARTg) | 17 (10/58) | 0 | 13 (9/70) |
| Case fatality rate (%) | 27.8 (15/54) | 1.7 (1/59) | 13.0h) (9/69) |
a) Values in mean (min-max) or percentage and proportion. b) The 52 healthy controls are not included. c) Defined as jaundice/ bilirubine> 50 μmol/L d) Defined as bleeding disturbances/ hemolysis e) Defined as GCS ≤ 11, convulsions or confusion f)CD4 T-cell count were only obtained in 8 (HIV only) and 11 (HIV + malaria) patients. g) Effective ART is defined as undetectable HIV-RNA levels. h) One patient died of non-malarial cause, he was excluded