Table 3.
Pre- and Post-treatment mean PedsQL scores of patients in groups A and B and of healthy controls: child self-report
| Healthy controls (N = 999) | Group A (N = 62) | Group B (N = 22) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Pre-treatment | Pre-treatment vs. Healthy controls | After CR | After CR vs. Healthy controls | After CR vs. Pre-treatment | Pre-treatment | Pre-treatment vs. Healthy controls | 12 months after initiation of treatment | 12 months after initiation of treatment vs. Healthy controls | 12 months after initiation of treatment t vs. Pre-treatmen | ||
| Total score | 83.6 ± 12.1 | 81.9 ± 11.6 | P 0.301 ES −0.14 [− 0.39, 0.12] | 88.5 ± 10.1 |
P 0.024 ES 0.41 [0.15, 0.67] |
P 0.001 ES 0.61[0.24, 0.97] |
83.0 ± 11.1 |
P 0.527 ES − 0.05 [− 0.47, 0.37] |
83.5 ± 8.6 |
P 0.469 ES − 0.01 [− 0.43, 0.41] |
P 0.916 ES 0.06 [− 0.55, 0.67] |
| Physical Health Domain | 85.2 ± 14.8 | 88.4 ± 10.8 | P 0.257 ES 0.22 [− 0.04,0.48] | 93.8 ± 8.4 |
P < 0.001 ES 0.59 [0.33, 0.85] |
P 0.002 ES 0.56 [0.2, 0.92] |
90.2 ± 8.8 |
P 0.229 ES 0.34 [− 0.08, 0.76] |
90.3 ± 9.2 |
P 0.205 ES 0.35 [− 0.08, 0.77] |
P 0.971 ES 0.01 [−0.6, 0.62] |
| Psychosocial Health Domain | 83.4 ± 13.2 | 79.7 ± 13.2 |
P 0.029 ES − 0.28 [− 0.54, − 0.22] |
86.7 ± 11.7 |
P 0.028 ES 0.25 [− 0.01, 0.51] |
P 0.002 ES 0.56 [0.2, 0.92] |
80.6 ± 12.5 |
P 0.237 ES − 0.21 [− 0.64, 0.21] |
81.3 ± 9.9 |
P 0.195 ES − 0.16 [− 0.58, 0.26] |
P 0.916 ES 0.06 [− 0.55, 0.67] |
| Emotional Functioning | 76.5 ± 18.9 | 73.2 ± 17.2 |
P 0.156 ES − 0.18 [− 0.43, 0.08] |
81.2 ± 17.9 |
P 0.024 ES 0.25 [− 0.01, 0.51] |
P 0.007 ES 0.46 [0.1, 0.82] |
74.3 ± 18.1 |
P 0.535 ES − 0.12 [− 0.54, 0.31] |
74.7 ± 15.3 |
P 0.463 ES − 0.1 [− 0.52, 0.33] |
P 0.953 ES 0.02 [− 0.58, 0.63] |
| Social Functioning | 88.9 ± 15.7 | 82.7 ± 16.2 |
P 0.003 ES − 0.39 [− 0.65, − 0.14] |
88.8 ± 13.5 |
P 0.899 ES − 0.01 [− 0.26, 0.25] |
P 0.033 ES 0.41 [0.05, 0.77] |
83.4 ± 13.4 |
P 0.027 ES − 0.35 [− 0.77, 0.07] |
85.2 ± 14.3 |
P 0.182 ES − 0.24 [− 0.66, 0.19] |
P 0.607 ES 0.06 [− 0.55, 0.67] |
| School Functioning | 84.9 ± 13.6 | 83.3 ± 14.3 |
P 0.375 ES − 0.12 [− 0.37, 0.14] |
90.1 ± 11.2 |
P 0.001 ES 0.39 [0.13, 0.64] |
P 0.002 ES 0.53 [0.17, 0.89] |
84.1 ± 15.3 |
P 0.809 ES − 0.06 [− 0.48, 0.36] |
84.1 ± 10.2 |
P 0.722 − 0.06 [− 0.48, 0.36] |
P 0.596 ES 0 [− 0.61, 0.61] |
Scores are presented with SDs, and ESs with their 95% confidence intervals [in intervals]. ES calculations and paired t tests were conducted for for completers at after treatment, by comparing scores with those at baseline
Appendices: ES, effect size; P, p value; CR, complete response