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. 2020 Jan 21;15:23. doi: 10.1186/s13023-019-1258-3

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Graphical overview of clinical organ manifestations in Tuberous Sclerosis Complex (TSC). Prevalences are given in parentheses after each manifestation. *Prevalence of LAM is given for female patients as there is a high gender-dependency. Prevalences for the majority of manifestations change with age. For sources of the prevalences, please refer to section 3.1 of the manuscript. ADHD = attention deficit hyperactivity disorder, AML = angiomyolipoma, LAM = lymphangioleiomyomatosis, PNET = pancreatic neuroendocrine tumor, SEGA = subependymal giant astrocytoma, SEN = subependymal nodules. Graphic adapted from “Female_shadow_template.svg” and “Girl_diagram_template.svg”, available in the public domain and accessible at https://commons.wikimedia.org/wiki/Human_body_diagrams (original author: Mikael Häggström)