Table 2.
Average combined behavioral score in each group at different post-injury times
| Post injury (wk) | Control | MSCs | Rho | Ad-HIF-MSCs | Rho + Ad-HIF-MSCs |
|---|---|---|---|---|---|
| 1 | 22.14±1.36 | 29.15±1.93* | 30.38±3.96** | 35.67±1.82** | 36.28±4.26** |
| 3 | 36.19±1.52 | 45.2±3.56** | 62.52±4.52** | 57.34±3.64** | 67.39±5.68**## |
| 6 | 50.65±1.09 | 60.34±5.46** | 75.65±5.32** | 78.39±3.58** | 83.67±6.35**## |
| 12 | 53.39±1.63 | 67.56±6.38** | 81.27±7.58** | 83.36±5.21** | 94.61±8.35**## |
*P < 0.05, **P < 0.01, vs. control group; ##P < 0.01, vs. Ad-HIF-MSCs group. Data are expressed as the mean ± SD (n = 3; two-way repeated-measures analysis of variance followed by Tukey’s post hoc test). The value represents the effect of repairing acute spinal cord injury. The higher the value, the better the effect. Ad: Adenovirus; Con: control; HIF: hypoxia-inducible factor; MSCs: mesenchymal stem cells; Rho: rhodioloside.