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. 2020 Jan;57:203–216. doi: 10.1016/j.ymben.2019.11.007

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 7 — Images obtained by electron microscopy of cells engineered to overexpress lipid modifying genes. Samples were taken at day 6 of batch culture and observed using a Jeol 1230 transmission electron microscope and images were captured using a Gatan One View 16mp camera. Monoclonal and host cell pools (A) and cB72.3 and FcFP expressing cells (B) were imaged and representative images are shown for all cells included in this study. Figure (C) shows images from CHO-SCD1^POOL (i) and CHO-SCD1^HIGH (ii, iii and iv) of membrane protrusions observed frequently in these cells.