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. 2019 Dec 19;4(24):e126054. doi: 10.1172/jci.insight.126054

Figure 4. Effects of RN168 on CD4+FoxP3+ Tregs assessed by flow cytometry.

Figure 4

(A) Tregs. Baseline mean (±SD) values: placebo 44.2733 (7.5852) (n = 7); RN168 1 mg 45.7443 (22.0758) (n = 8); RN168 3 mg 49.8629 (15.9373) (n = 9); RN168 6 mg 50.5640 (15.3193) (n = 5); RN168 8 mg 63.3043 (31.3837) (n = 8). (B) Ratio of Tregs to CD4+ effector memory T cells. Baseline mean (±SD) values: placebo 0.650 (0.248) (n = 7); RN168 1 mg 0.776 (0.348) (n = 8); RN168 3 mg 1.104 (0.483) (n = 9); RN168 6 mg 0.522 (0.216) (n = 5); RN168 8 mg 0.774 (0.377) (n = 8). (C) Ratio of Tregs to CD8+ effector memory T cells. Baseline mean (±SD) values: placebo 0.931 (0.830) (n = 7); RN168 1 mg 0.588 (0.304) (n = 8); RN168 3 mg 1.206 (0.824) (n = 9); RN168 6 mg 0.604 (0.321) (n = 5); RN168 8 mg 0.767 (0.655) (n = 8).