(A) Heatmap of gene expression change of the top 50 differential protein-coding genes in CD4+ T cells. (B) Changes in expression of select immune-related genes (CCR6, RANK, Tbet, and GATA3) in CD4+ T cells. (C) Heatmap of change in expression of top 50 differentially expressed protein-coding genes in CD8+ T cells. (D) Changes in expression of select immune-related genes (LTK, CCR4, CD40LG, and KLRB1) in CD8+ T cells.