Rod circuit schematics of control and transgenic mice. A–E, Circuit diagrams depicting WT (A) and targets of disruption in transgenic mice (B–E). B, G2 mice (cpfl3 and KO) have disrupted cone circuits leaving only functional rod circuits. C, G2::Cx36 mice have both disrupted cone circuits and disrupted Cx36-dependent rod pathways (secondary pathway and ON branch of the primary pathway). D, G1 mice have disrupted rod circuits leaving only functional cone circuits. E, G1::G2 mice have disrupted rod and cone circuits. R, rod; C cone; black resistors, Cx36 gap junctions; RB, rod bipolar; AII, amacrine AII; ON CB, ON cone bipolar; OFF CB OFF cone bipolar; GC ganglion cell; green, primary path circuit; blue, secondary path and cone path circuit; pink, tertiary path circuit.